Manufacturing Technique and Property Evaluations of Biodegradable Nanofiber Membrane for Medication

Jia-Horng Lin, Chih-Kuang Chen, Wei-Jen Lin, Chien-Lin Huang, Wen-Cheng Chen, Ching-Wen Lou


This study formulates polyvinyl alcohol (PVA) solution and Bletilla striata (BS) extractive with various mixing ratios into various mixtures, which are then electrospun into composite membrane with settings of a specified voltage of 12 kV, collection distances of 12 cm, PVA concentrations of 12 wt%, and BS additions of 0.1, 0.3, and 0.5 %. The various PVA/BS mixtures are tested for conductivity and viscosity, and the resulting electrospinning composite membranes are evaluated with surface morphology analysis, Fourier transform infrared spectra (FT-IR), and diameter analysis. The test results show that the content of BS is proportional to the conductivity of the mixtures. The addition of *BS decreases the diameter of the electrospinning fibers, while also creating beads on the fibers. The diameter of the electrospinning fibers increases as a result of the increasing concentration of PVA solution or the increasing collection distance. The FT-IR results indicate the absent chemical reaction between PVA and BS.


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