Computational Simulation of Studying Zika Virus: from Macroscale to Nanoscale

Xiu-guo ZHAO, Jin-hui WU,, Yao-hua DU, Zong-xing ZHANG, Ying YI, Li-mei HAO, Ming-xi HU, Xin-xi XU, Jian-cheng QI


Zika virus (ZIKV) recently outbreaking from 2015 to 2016 over Americas has attracted a global health concern. As a member of family of Flaviviridae, Zika virus a positive-sense single-stranded RNA virus is highly likely associated with birth defects (primary microcephaly) and neurological complications. However, computer simulation method is widely used to study spread of Zika virus at macroscale level and related-structures and vaccines of Zika virus at atomic level, which also provides insights into Zika virus. Here the current advancements were reviewed and future developments were discussed.


Zika virus, Computational simulation, Molecular dynamics simulation


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